OPTIMIZING PRP FOR MSK CONDITIONS

Platelet-rich plasma (PRP) is an Orthobiologics treatment and is very becoming very popular as a potential alternative treatment for various musculoskeletal conditions. The physiologic role of platelets in the healing cascade provides clarity regarding its potential as it releases various growth factors such as platelet-derived growth factor (PDGF), transforming growth factor beta-1 (TGF-β1), and vascular endothelial growth factor (VEGF). However, there is a lack of standardization, and one of the main reasons is the amount of possible variables in preparing the prp; the type of centrifugation, platelet count, presence or absence of leukocytes and red blood cells, as well as the use of an activating agent, number of spins, photo activation, whether or not the procedure is imageguided, whether the patient has been metabolically approached All these variables make for a wide variety of possibilities for final products. The purpose of this presentation is to bring what studies tell us about each of them so far

Author(s): Victor Pacheco

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