Mouth dissolving tablets: An overview on future compaction in oral formulation technologies

The desire of improved palatability in orally administered products has prompted the development of numerous formulations with improved performance and acceptability. Orally Disintegrating tablets (ODTs) have received ever-increasing demand during the last few decades, and the field has become a rapidly growing area in the pharmaceutical industry. The unique property of mouth dissolving tablet is that they are rapidly disintegrating and/or dissolving and release the drug as soon as they come in contact with saliva, thus obviate the requirement of water during administration. This article reviews the earlier applications and methodologies of taste masking and also emphasize on the recent developments and approaches of bitterness reduction for orally used pharmaceuticals. Apart from the conventional methods of fabrication, this review also provides the detailed concept of some unique patents; technologies developed and marketed formulations of Mouth Dissolving Tablets (MDTs).

Author(s): Kamal Saroha, Pooja Mathur, Surender Verma, Navneet Syan and Ajay Kumar

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