Microwave Assisted One Pot Synthesis of Substituted Dihydropyrimidine-2(1H)
ones using 5-sulphosalicyclic acid as a Catalyst

Nazeruddin N. Gulam Mohammed; Mahesh S. P; harpatte

Abstract

Microwave Assisted One Pot Synthesis of Substituted Dihydropyrimidine-2(1H) ones using 5-sulphosalicyclic acid as a Catalyst

An efficient microwave assisted one pot synthesis of Dihydropyrimidine-2 (1H) from aldehydes, diketones and urea/thiourea using 5-sulphosalicylic acid as a catalyst is described, compared to classical Biginielli reaction the new method has advantage of good yield and short reaction time

Author(s): Nazeruddin N. Gulam Mohammed , Mahesh S. Pandharpatte

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