ISSN : 2575-7725
Organoids enable the study of organs in 3D models, allowing
modification of genetic and environmental factors that influence
ultimate function. Organoids are essentially microcosms
of organs, recapitulating organ function. Derived from stem
cells, organoids are propagated in culture in three-dimensional
cell clusters for later experimentation. Organoids develop
upon the culture of pluripotent cells - meaning that organoids
may develop into any of a variety of different mature cell types
when placed in an amenable environment for growth- hES (human
embryonic stem) and hiPS (human induced pluripotent
stem) cells. The stem cell origins of organoids enables them
to develop into a multitude of different organoid types.
Journal of Stem Cell Biology and Transplantation received 80 citations as per Google Scholar report