Abstract

Kidney Injury and COVID-19

Extracellular Vesicles (EVs) are lipid bilayer particles released by different cells that provide a non-invasive real-time snapshot of the condition of these cells in tissue. EVs contain mRNA,

miRNAs, proteins, and metabolites, among other things. As a
result, EVs have the potential to be used to develop liquid
biopsy-based biomarkers for illness diagnosis. The current study
used liquid chromatography/mass spectrometry to analyse the
metabolome of urine EVs in rats with kidney injury caused by
cisplatin and puromycin aminonucleoside to find possible
biomarkers that represent the kind and amount of harm in druginduced
nephrotoxicit.


Author(s): Jason Blanc

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