Instructions for Authors to Prepare Manuscript for Journal of Genomics and Gene Study Pratibha Nallari

Organization of the Manuscript:

Most articles published in IMedPub Journals will be organized into the following sections: title, authors, affiliations, abstract, introduction, methods, results, discussion, references, acknowledgments, and figure legends. Uniformity in format will help readers and users of the journal. We recognize, however, that this format is not ideal for all types of studies. If you have a manuscript that would benefit from a different format, please contact the editors to discuss this further. Although we have no firm length restrictions for the entire manuscript or individual sections, we urge authors to present and discuss their findings concisely.

Title (max 125 characters):

The title should be specific to the study yet concise, and should allow sensitive and specific electronic retrieval of the article. It should be comprehensible to readers outside your field. Avoid specialist abbreviations if possible. Titles should be presented in title case, meaning that all words except for prepositions, articles, and conjunctions should be capitalized. If the paper is a randomized controlled trial or a meta-analysis, this description should be in the title.

Examples: Climate Change and Increased Spread of Malaria in Sub-Saharan Africa A Cluster-Randomized Controlled Trial of a Nurse-Led Intervention after Stroke Please also provide a brief “running head” of approximately 40 characters. Authors and Affiliations: Provide the first names or initials (if used), middle names or initials (if used), surnames, and affiliations—department, university or organization, city, state/province (if applicable), and country—for all authors. One of the authors should be designated as the corresponding author. It is the corresponding author’s responsibility to ensure that the author list, and the summary of the author contributions to the study are accurate and complete. If the article has been submitted on behalf of a consortium, all consortium members and affiliations should be listed after the Acknowledgments. (For authorship criteria, see Supporting Information and Materials Required at Submission)

Abstract: The abstract is divided into the following four sections with these headings: Title, Background, Methods and Findings, and Conclusions. It should contain the all following elements, except for items in square brackets, which are only needed for some study types. Please use the same format for abstracts submitted as presubmission inquiries.

Title: This should be a clear description of the paper’s content. The design must be present for randomized controlled trials or systematic reviews or meta-analyses and should be included for other study types if useful.

Background: This section should describe clearly the rationale for the study being done. It should end with a statement of the specific study hypothesis and/or study objectives.

Methods and Findings: Describe the participants or what was studied (eg cell lines, patient group; be as specific as possible, including numbers studied). Describe the study design/intervention/main methods used/What was primarily being assessed eg primary outcome measure and, if appropriate, over what period.

Conclusions: Provide a general interpretation of the results with any important recomendations for future research. [For a clinical trial provide any trial identification numbers and names (e.g. trial registration number, protocol number or acronym).]

Introduction: The introduction should discuss the purpose of the study in the broader context. As you compose the introduction, think of readers who are not experts in this field. Include a brief review of the key literature. If there are relevant controversies or disagreements in the field, they should be mentioned so that a non-expert reader can delve into these issues further. The introduction should conclude with a brief statement of the overall aim of the experiments and a comment about whether that aim was achieved. 

Methods: This section should provide enough detail for reproduction of the findings. Protocols for new methods should be included, but well-established protocols may simply be referenced. Detailed methodology or supporting information relevant to the methodology can be published on our Web site. This section should also include a section with descriptions of any statistical methods employed. These should conform to the criteria outlined by the Uniform Requirements, as follows: “Describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as confidence intervals). Avoid relying solely on statistical hypothesis testing, such as the use of P values, which fails to convey important quantitative information. Discuss the eligibility of research participants. Give details about randomization. Describe the methods for and success of any blinding of observations. Report complications of treatment. Give numbers of observations. Report losses to observation (such as dropouts from a clinical trial). References for the design of the study and statistical methods should be to standard works when possible (with pages stated) rather than to papers in which the designs or methods were originally reported. Specify any general-use computer programs used.”

Results: The results section should include all relevant positive and negative findings. The section may be divided into subsections, each with a concise subheading. Large datasets, including raw data, should be submitted as supporting files; these are published online alongside the accepted article. The results section should be written in past tense. 

As outlined in the Uniform requirements, authors that present statistical data in the Results section, should “...specify the statistical methods used to analyze them. Restrict tables and figures to those needed to explain the argument of the paper and to assess its support. Use graphs as an alternative to tables with many entries; do not duplicate data in graphs and tables. Avoid nontechnical uses of technical terms in statistics, such as “random” (which implies a randomizing device), “normal,” “significant,” “correlations,” and “sample.” Define statistical terms, abbreviations, and most symbols.” 

Discussion: The discussion should be concise and tightly argued. It should start with a brief summary of the main findings. It should include paragraphs on the generalisability, clinical relevance, strengths, and, most importantly, the limitations of your study. You may wish to discuss the following points also. How do the conclusions affect the existing knowledge in the field? How can future research build on these observations? What are the key experiments that must be done?

References: Only published or accepted manuscripts should be included in the reference list. Meetings, abstracts, conference talks, or papers that have been submitted but not yet accepted should not be cited. Limited citation of unpublished work should be included in the body of the text only. All personal communications should be supported by a letter from the relevant authors.

Author(s): Pratibha Nallari

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