Inflammatory Myofibroblastic Tumor of the Lung: A Rare Case

Inflammatory myofibroblastic tumor is a rare, low-grade neoplasm, found mainly in lung, pelvis and abdomen. Fever, cough, shortness of breath, pleuritic chest pain, hemoptysis and weight loss are common clinical manifestations. In one third, the tumor is incidental finding. Imaging shows a nodule or peripheral mass, mainly in lower lobes. The lesion is solitary, rarely numerous. Immunohistochemically, the tumor is SMA (+) and ALK (+) in 50% of cases. Treatment of choice is surgical resection, whereas corticosteroids, non-steroid anti-inflammatory drugs, Tyrosine Kinase Inhibitors (TKIs) for ALK (+) tumors, chemotherapy and radiotherapy are included in treatment options in cases that are not eligible for surgical resection. In this article, we present a rare case of inflammatory myofibroblastic lung tumor in an elderly man, with remission after treatment with non-steroidal antiinflammatory drugs.

Author(s): Vasiliki Petta* , Athanasios Zetos, Danai Bisirtzoglou, Maria Salomidou, Charalambos Marketos

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