In vitro Antifungal Potentials of Bioactive Compounds Heptadecane, 9- hexyl and Ethyl iso-allocholate isolated from Lepidagathis cristata Willd. (Acanthaceae) leaf

Objective: To identify bioactive compounds Heptadecane, 9- hexyl and Ethyl iso-allocholate from Lepidagathis cristata Willd.( L. cristata) leaf to assess antifungal potentials of the isolated compounds Methods: Aqueous extracts of L. cristata leaves were used for this study. The major bioactive compounds isolated were tested for antifungal activities. Results: The major bioactive compounds Heptadecane, 9- hexyl and Ethyl iso-allocholate were isolated from the leaves of L. cristata and these compounds were tested for antifungal potentials and found to be highly effective to plant pathogenic fungi Colletotrichum fulcatum NCBT 146, Fusarium oxysporum NCBT 156 and Rhizoctonia solani NCBT 196 as well as for the human pathogenic fungi Curvularia lunata MTCC 2030 and Microsporum canis MTCC 2820. Conclusions: The results justify the antifungal potentials of both plant and human pathogenic fungi. The plant bioactive compounds will be helpful in herbal antifungal formulations.

Author(s): Maghdu Nainamohamed Abubacker and Palaniyappan Kamala Devi

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