In differential diagnosis of dementia -application of easy Z-score imaging system in single photon emission computed tomography Brain perfusion scan.

Background: Application of easy Z score imaging system (eZIS) on brain perfusion SPECT images for quantitative evaluation of rCBF has attempted to explore the differential diagnosis of dementia with various degenerative diseases and to evaluate discrimination of early Alzheimer’s disease (AD) from other types of dementia. Methods: This retrospective study was done with various degenerative diseases that underwent brain perfusion SPECT using 99mTc ethyl cysteinate dimer were included. Results: Brain perfusion SPECT   was performed in 58 patients (M/F = 48/10) with mean age of 61.2±10.4 years (41-90). Decreased rCBF was observed in the area suspected early AD in 20 cases (34%) and in the frontal gyrus and insula in 10 cases (17%). And decreased rCBF was observed in occipital lobe

Author(s): Nasreen Sultana

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