Histopathological Study of Upper Gastrointestinal Endoscopic Biopsies-1 Year Prospective Study

Abstract Objective: Endoscopy of the gastrointestinal tract is a simple safe and well tolerated procedure, the visualisation of the site with biopsy leads to the early detection of the pathologic process and institution of appropriate therapy. The present study was done to find out the morphological pattern and frequencies of lesions reported in upper gastrointestinal tract endoscopic biopsy specimens. Methods: This was a prospective study conducted on 200 Upper Gastrointestinal Tract endoscopic biopsies in the Department of Pathology from November 2015 to November 2016. Results: Out of 200 endoscopic biopsies, Male to Female ratio was 1.5:1 and age range of 16-95 years was observed. There were 48 cases (24%) from esophagus, 22 (11%) cases from GE junction, 110 (55%) cases from stomach and 20 cases (10%) from duodenum. 13 cases revealed no pathology on histopathology. 93 cases (46.5%) cases were neoplastic and 107 (53.5%) were non neoplastic. On histopathologic examination Chronic Gastritis with 48 cases (24%) was the most common lesion found while Squamous cell carcinoma of esophagus with 35cases (17.5%) was the most frequently diagnosed malignant lesion. Conclusion: Endoscopy is incomplete without biopsy, so combination of methods provides a powerful diagnostic tool for better patient management. Keywords: Endoscopy; Upper GIT; Biopsy; Histopathology

Author(s): Bhat N, Sheikh BA,Mir JN, Reshi R, Wani LA and Farooq S

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