Green Synthesis of Tecoma Stans Flower and Leaf Extracts: Their Characterization and Anti-OProliferative Activity in Colorectal Cancer Cell Lines.

Since times immemorial, many plant species were utilized to cure severe ailments. A wide range of diversification has been observed in various medicinal plants which indeed able to cure several deadly diseases. Presence of secondary metabolites is a high priority for their medicinal characteristics. In this study, we focused on T.stans (Yellow bells), a shrub that grows profoundly in tropical and sub- tropical regions. Despite many studies the medicinal values of this plant species, yet not much research has been done in the cancer treatment and nanomedicine. Green synthesized silver Nano-particles is an eco-friendly approach to deliver the drug to the target size. Nano appearance is an add-on advantage of these compounds- hence emerging in the field of medicine. Our current study, focused on Colorectal cancer, is the 4th deadliest one globally. Hence the synthesized AgNPs of T.stans flower and leaf extracts showed cytotoxic and wound healing properties on colorectal cancer cell lines (HCT 116 and SW 480). Synthesis of AgNPs confirmation is done by UV-Vis spectrophotometry and Particle size analyzer. All the results showcase the beneficial effects of AgNP synthesized plant extracts and may be used as a novel medicine in the field of chemotherapy.

Author(s): Kousalya lavudi

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