Extraction and Evaluation of Hypoglycemic and Wound Healing Potential of Hydro-Ethanolic Extract of Alhagi pseudalhagi Wild

Objective: The present investigation envisaged to evaluate antidiabetic and wound healing potential of hydro-ethanolic extract of Alhagi pseudalhagi (family: Leguminosae) plant from Chambal region.
Experimental section: The hydro-ethanolic extract of A. pseudalhagi obtained by hot Continuous extraction was subjected to phytochemical examination and pharmacological screening for antidiabetic activity in male wistar rats after intraperitoneal administration using 18 h rat fasted model, oral glucose tolerance test and STZ induced diabetic rat model. The wound healing activity was evaluated through excision wound model and the progressive change in wound area was monitored planimetrically by tracing the wound margin on graph paper.
Results: The hydro-ethanolic extract of A. pseudalhagi observed containing the presence of different phyto-constituents of alkaloids, carbohydrates, glycosides, protein and amino acids, phenolic compounds, tannins which has potential antidiabetic and wound healing activity on standard pharmacological models Conclusion: The observations from present study suggest A. pseudalhagi as a promising candidate with potential antidiabetic activity having wound healing property as well. It may prove to be effective in the treatment of diabetic wound healing.

Author(s): Anupam K Sachan, Ch.V.Rao and Nikhil K Sachan

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