Emulgel: A no Refuseable Formulation to Improve Solubility, Penetration and Percentage of Aceclofenac Release for Suppressing Prostaglandins E2 Synthesis

Aim and Objective: Formulation, development and evaluation of Aceclofenac emulgel. Method: simple way aceclofenac dissolve in oil base then add this oil base into previously prepared gel lead to provide aceclofenac emulgel. Result and Discussion: Aceclofenac have better therapeutic action than diclofenac diethyl amine but is water insoluble. While ointment and gel like formulations are not preferred by patient as have greasiness, less effective, less shelf-life etc. To overcome these problems aceclofenac emulgel was formulated which improves solubility, permeability and finely bioavailability of aceclofenac which render it more use as topically as analgesic than diclofenac diethyl amine. This research was shown by researchers in terms of various parameters in this article.

Author(s): Ashara Kalpesh C, Solanki Jignesh, Mendapara Vishal P and Mori Nitin M

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