Efficient one-pot three-component synthesis of thiazolyl pyrazole derivatives
under conventional method

Velpula Ravibabu; Banothu Janardhan; Gali Rajitha; Bavantula Rajitha

Abstract

Efficient one-pot three-component synthesis of thiazolyl pyrazole derivatives under conventional method

A series of 4-substituted-N-((1,3-diaryl-1H-pyrazol-4-yl)methylene)thiazol-2-amines were synthesized by the one-pot three component condensation of substituted phenacyl bromide / 3-(2-bromoacetyl)-2H-chromen-2-one with 1,3- diaryl-1H-pyrazole-4-carbaldehyde and thiourea under conventional heating in absolute ethanol using catalytic amount of acetic acid with good yields. The structure of the compounds was established by their spectral studies

Author(s): Velpula Ravibabu, Banothu Janardhan, Gali Rajitha and Bavantula Rajitha

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