Do We Need to Improve Oral Chemotherapy Adherence Monitoring? A Case Report of Temozolomide Overdose

Accidental overdose of chemotherapy is an infrequent situation; in particular for intravenous treatments, that have guidelines that strictly address their correct prescription, preparation and administration. On the other hand, the correct use of oral antineoplastic drugs is only marginally addressed. This fact can lead to medication errors and toxicities, sometimes with fatal consequences. We describe the clinical course of a 40 years old man, affected by neuroendocrine tumor, who assumed a double dose of Temozolomide because of a wrong read hand prescription.

Author(s): Federico Paolieri, Andrea Sbrana, Francesco Bloise, Elisa Biasco, Luca Galli and Andrea Antonuzzo

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