Comparison between Dynamic Contrast-Enhanced Magnetic Resonance (DCE-MR) and Dynamic Contrast-Enhanced Ultrasound (DCE-US) in the Imaging of Pediatric Extra-Cranial Tumor

Post injection data analysis was conducted using Functool software. A region of interest (ROI) was placed in the lumen of the nearest large artery to evaluate the arterial input function. Consecutively, perfusion and tissue-blood ratio were calculated and colour mapping was generated. ROIs were drawn around its highest vascularized area and different parts of the tumor or mass according to the different distribution pattern on the colour map.

Signal intensity (SI) values were measured in operator-defined ROIs. The SI values derived from the ROIs were plotted against time as time intensity curve (TIC). TIC was plotted and the enhancement patterns were divided into type 1, 2 and 3 curves. Type 1 curve showed a gradual continual persistent rise after the arrival of the arterial bolus (progressive). Type 2 curve showed relatively rapid increase after the arrival of the arterial bolus and then became plateau or static. Under Type 3 curve, TIC demonstrated a sharp rise of contrast enhancement in the tumor after the arrival of the arterial bolus and then followed by a steeper wash-out (Figure 1).

Author(s): Wendy WM Lam, Department of Radiology, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, PR ChinaWendy WM Lam, Department of Radiology, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, PR China

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