Comparative in vitro release study of some commercially available paracetamol tablets

A tablet is a pharmaceutical dosage form. It comprises of active substances and excipients. Various brands of some dosage forms are available in the market with the common claim that they are all bioequivalent. The main objective of the present study was to conduct the comparative dissolution studies of various brands of same dosage forms to determine whether all the formulations used were equivalent or significantly different. Five different brands of Paracetamol of 500 mg conventional tablets from different manufacturers were selected in the study and dissolution testing in 7.8 pH Phosphate buffer was conducted from each brands for 30 mins. By using dissolution testing apparatus USP type-II

Author(s): Syed Anees Ahmed, Niharika Pal, Garima Verma and Arvind Singh

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