Comparative Evaluation of Antimicrobial Activities of the Members of Solanaceae

The present study deals with the antimicrobial activities of the chloroform, ethyl acetate and methanol leaf extracts of, Solanum anguivi Lam., S. nigrum Linn., S. pubescens Willd., S. surratense Burm.F., S. torvum Swartz., and S. trilobatum Linn. by following agar well diffusion method against human pathogens: Staphylococcus aureus MTCC 96, Micrococcus luteus ATCC 4698, Vibrio cholerae ATCC 14035 and Klebsiella pneumoniae MTCC 109, Candida albicans MTCC 183, Candida parapsilosis MTCC 2509 and Candida tropicalis MTCC 184. All the ethyl acetate extracts of the selected members of Solanaceae of the selected species of Solanaceae were effective against four human bacterial species such as S. aureus, M. luteus, V. cholerae, and K. pneumoniae, and three fungal species of C. albicans, C. parapsilosis and C. tropicalis. Among these S. anguii leaf extract showed maximum antimicrobial activity against the test pathogens. The results showed that the plant could be further explored for possible antibiotic and antifungal agents and provides preliminary scientific validation of the traditional medicinal use of this plant.

Author(s): J. Gandhiappan, R. Rengasamy

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