Keloid is denominated as a benign, fibro-proliferative neoplasm arising due to anomalous wound healing or a fibroblastic connective tissue reaction to diverse contributory factors such as surgical intervention, burns, trauma, inflammation, foreign body reaction or endocrine dysfunction. Occasionally, keloid may occur spontaneously. As keloid emerges due to aberrant wound healing, in contrast to stages of normal wound healing, keloid demonstrates a prolonged fibroblastic phase with unchecked fibroblastic proliferation. Scars with keloid are benign and mandate therapy due to relief of clinical symptoms or cosmetic concerns. Although multiple therapeutic modalities are adopted, a singular, optimal treatment option for alleviating keloid remains an enigma.
Journal of Medical Oncology received 134 citations as per Google Scholar report