In recent time Club is become a main place of crimes like rape, murder, robbery, etc in metro cities. These types of social crimes are done mostly by using the newly invented medicines. Club crimes are type of assaults where the victim and the offender are in, or have been in, some form of personal social relationship, ranging from a first get together to an established relationship. Club drugs can incapacitate a person for a period of time and cause memory loss. These drugs may be colorless and odorless; their taste is easily masked. They may be in liquid form or dissolve easily in liquid. After ingestion, effects can occur immediately or within 15 to 30 minutes. The drugs described here are often called “date rape drugs” because they quickly increase a person’s vulnerability to sexual assault.[1],[2]Most common Club drugs are Flunitrazepam, Ketamine and GHB