Biological studies of a novel azo based Heterocyclic Schiff base and its transition metal complexes

A new heterocyclic Schiff base ligand bis(2-(pyridin-2-ylimino)phenyl)-4,4'-(diazene-1,2- diyl)dibenzoate (BPPD, L) and its metal complexes with divalent transition metal ions viz., Co(II), Ni(II), Cu(II) and Zn(II) have been synthesized and characterized through IR, NMR and elemental analysis. The ligand and its complexes have been screened for the antibacterial activities towards bacteria Staphylococcus aureus (gram positive) and Escherichia coli (gram negative), and antifungal activities towards fungi Aspergillus niger and Candida albicans. The results showed that the complexes have higher antimicrobial activities than the ligand. The order of antimicrobial activities was Cu(II)L> Zn(II)L>Ni(II)L>Co(II)L>L

Author(s): Hemant Kumar and Ram Pal Chaudhary

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