Application of Painless Dialysis in Blood Purification

Objective: In this study, dexmedetomidine was used in the process of dialysis to make patients fall asleep naturally, relieve pain, improve the quality of dialysis and improve the treatment outcomes.

Methods: The loading dose 1 ug/kg/h of dexmedetomidine was injected intravenously on the patient's body when the patient is treated. After adjusting the maintenance dose was 0.6~0.8 ug/kg/h, the dexmedetomidine was stopped 1.5 hours before the end of hemodialysis. The BIS value (bispectral index, reflecting the monitoring of anesthesia depth) was monitored in the whole process. The BIS value of the patients was less than 80 during hemodialysis. The BIS value and RASS score were recorded at 1 h, 2 h and the end of hemodialysis. After awakening, the patients' satisfaction was scored.

Results: All the patients entered into a state of natural sleep after using dexmedetomidine. The dialysis process was stable, and the patients were conscious after awakening. At the same time, most of the patients felt painless puncture, comfortable in body and mind, they all entered a deeper sleeping during dialysis.

Conclusion: The method is safe and effective, the effect is ideal and the patient’s satisfaction is high. This method is used for patients who are sensitive to pain, have trouble sleeping, and are unable to tolerate dialysis.

Author(s): Xiaojing Zhu, Meixia Meng, Li Zhang , Ling Zheng, Yongping Shao, Yuan Zhang

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