Ajuga bracteosa wall: A review on its ethnopharmacological and phytochemical studies

The aim of the study is an attempt to investigate out Phytochemical and ethnopharmacological application of Ajuga bracteosa wall benth. to treat cancer, diabetes, gastrointestinal disorders, worm infestations, urinary disorders , fungal infections, inflammation and tuberculosis in folk medicines. Data was collected from various internet websites and libraries of Council of Scientific and Industrial Research Institutes as CIMAP (Central Institutes of Medicinal and aromatic plant) Lucknow, CDRI (Central Drug Research Institute) Lucknow, NBRI (National Botanical Research Institute) Lucknow, NML (National Medical Library) New Delhi and Pharmacy Department, GGDU, Bilaspur, India. Various plant parts such as leaves, bark, stem and roots of Ajuga bracteosa have been used in ethno medicine to exploit its medicinal properties including astringent, hypoglycemia, gastrointestinal disorders, as anthelmintic, diuretic, antifungal, anti-inflammatory and antimycobacterial agents. Chemical compounds isolated from Ajuga bracteosa wall Ex. Benth have been proven to be pharmacological active against several major diseases including cancer, hypoglycemia and protozoal diseases. Preclinical studies indicate the therapeutic potential of crude extracts of Ajuga bracteosa wall Ex. Benth in the treatment of many microbial diseases, spasmodic activity and gastric ulcer. This review covers the pharmacological activities of some isolated chemical constituents of Ajuga bracteosa and preclinical studies on some crude extracts and pure compounds to explore novel bioactive compounds for therapeutic application.

Author(s): Akriti Pal, Mayank Jadon, Y. K. Katare, P.K. Singour, H. Rajak, P.K. Chaurasiya, U.K. Patil and R.S. Pawar

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