Activities of raw and partially boiled Quail (Coturnix Coturnix Japonica) eggs in increasing Megakaryocyte count among Aplasia-induced Mice

Megakaryocytes are among the largest cells in the body formed via multiple-staged megakaryopoiesis. These precursor cells release hemostasis-essential platelets into the circulation after undergoing thrombopoiesis. The significance of megakaryocytes and platelets is immediately apparent since a wide range of patients face morbidity and mortality from bleeding due to moderate to severe thrombocytopenia. In the tropics such as the Philippines, the mosquito borne viral disease dengue has become potentially deadly due to complications of plasma leaking, severe bleeding, and organ impairment. The bleeding mechanism for dengue remains poorly understood but the World Health Organization (WHO) specified thrombocytopenia with normal platelet function as a criterion. It has become potentially deadly due to its complications of plasma leakage, severe bleeding, and organ impairment. Quail eggs are packed with nutrients such as the B vitamins (B12, B9, and B3) which are vital for megakaryopoiesis. This study alleviates the negative effects of thrombocytopenia, the emerging cases of hemolytic disorders and dengue cases through the use of quail eggs. It has an impact on decreasing the need for blood transfusions in severe cases of dengue and hematopoietic disorders. It provides a less expensive and more accessible management for people who have problems in blood cell production and formation, especially megakaryocytes. Previous studies reported the hematopoietic effect of raw quail eggs however; the effect of food processing to its megakaryopoietic activity is unknown.

Author(s): Ordoño Herva

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