A systematic review investigating the factors that affect the participation of children and adolescents in vaccine research

Clinical research requiring participation of children and adolescents, including vaccine research, may be controversial and require greater ethical, legal, and cultural considerations than research involving adults. The aim of this review is to identify the factors (i.e. motivators, barriers, and solutions), which affect the participation (i.e. recruitment and retention) of children and adolescents in vaccine research. Children undergo cognitive development and experiences with vaccines have the potential to create future attitudes toward vaccines. This can influence future vaccine behaviour, including their participation in decision-making around adolescent vaccines, their decisions to vaccinate themselves when they are adults, and their decisions to vaccinate their own children. Interventions aimed at children, such as education, can create positive attitudes toward vaccines. Areas Covered: This review focuses on the lack of literature in this area and argues for more vaccine hesitancy research involving child and adolescent populations. In view of this, we directed a subjective investigation of young people, their folks and the youths' social insurance suppliers to distinguish likenesses and contrasts in inoculation perspectives and practices among these gatherings and to investigate the job of every partner in the antibody choice procedure. We at that point questioned these gatherings for their thoughts on potential mediations to improve antibody take-up that tended to distinguished obstructions in the immunization choice procedure.
Author(s): Lopa Banerjee

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