A Review paper on Worldwide growth of Pancreatic Cancer and its Treatment

The first pancreatic cancer (also called ductal carcinoma, adenocarcinoma
) was discovered in 1761 during 18th century by
Giovanni Battista Morgagni in his publication. Pancreatic cancer
is the Seventh leading Causes of cancer related to deaths
worldwide and highest mortality rate of all major cancers. For
all stages combined 91% of pancreatic cancer Patients will die
within Five years of diagnosis where only 9% will survive more
than five year. The large number of patients are die because
of liver failure from their living being taken tumor. Pancreatic
cancer remains one of the most lethal malignant neoplasm that
caused 432,242 new deaths In 2018. Then Globally in 2019
total 56,770 new cases have been reported and 45,750 new
deaths. The risk of developing Pancreatic cancer with most people
who develop pancreatic cancer are older than 45, 55 & 70%
are older than 65. However, Adults of any age can be diagnosed
with Pancreatic cancer. Pancreatic cancer occurs when cells in
your pancreas develop changes in their DNA(Mutation). A
cells DNA contains the instructions that tell a cell what to do.
These mutations tell the cells to grow uncontrollably and to
continue living after normal cells can form a tumor. When left
untreated , the pancreatic cancer cell can spread to nearby organs
and blood vessels and to distant parts of the body. Certain
risk factors are strongly linked to the disease including tobacc ,
smoking, diabetes mellitus alcohol abuse genetic factor & obesity.
The current treatment options for pancreatic cancer are
surgery, Lynparza is an oral targeted therapy, radiation therapy,
chemotherapy, targeted therapy and immunotherapy etc.

Author(s): Sutendra Desik Parauha

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