A Brief Review on Antitubercular Activity of Pharmacological Active Some Triazole Analogues

Triazole is a five member heterocyclic nucleus has attracted a wide consideration in exploration for the new remedial agents. This nucleus acts very important role in biological fields for various biologically active molecules. The chemistry of triazole compounds has expected considerable interest due to their synthetic and effective biological properties likes analgesic, antinflammatory, antioxidant, analeptic, sedatives, antianxiety, antimicrobials, anticonvulsant, anticancer, and other biological activities. There are various known drugs in market containing the triazole moiety likes voriconazole, triazolam, fluconazole, intraconazole, furacylin, alprazolam, etizolam etc. This review supplied a concise outline on triazole compounds as an antitubercular molecule. Because present antitubercular drugs are more toxic and multiple drug therapy is required. So it is significant to find out the triazole analogues with excellent antitubercular activity.

Author(s): Mohammad Asif*

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